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Hamostaseologie 1999; 19(01): 42-49
DOI: 10.1055/s-0038-1660376
DOI: 10.1055/s-0038-1660376
Übersichtsarbeiten/Review Articles
Hämodialyse bei Heparin-induzierter Thrombozytopenie
Further Information
Publication History
Publication Date:
27 June 2018 (online)
Zusammenfassung
Für die Hämodialyse von Patienten mit Heparin-induzierter Thrombozytopenie ist ein alternatives Antikoagulans erforderlich. Danaparoid-Natrium, rekombinante Hirudin-Derivate oder Argatroban scheinen geeignete Wirkstoffe zu sein, da sie eine Thrombenbildung wirkungsvoll unterdrücken, ohne das Blutungsrisiko wesentlich zu erhöhen. Da diese Ergebnisse auf Erfahrungen mit einer begrenzten Anzahl von Patienten basieren, sind größere prospektive Studien notwendig, um die besten Behandlungsmodalitäten für diese Erkrankungssituation festzulegen. Die Heparin-induzierte Thrombozytopenie sollte gleichwohl heute nicht mehr länger ein lebensbedrohliches Problem für dialysepflichtige Patienten sein.
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